Compound Name

Endrin

Stockholm Annex code I, IV
Key Annex I to the regulation are subject to prohibition (with specific exemptions) on manufacturing, placing on the market and use;
Annex II to the regulation are subject to restriction on manufacturing, placing on the market and use;
Annex III to the regulation are subject to release reduction provisions; and
Annex IV to the regulation are subject to waste management provisions.
Note that for some substances listed in Annex I, specific exemptions on the prohibition of their use, manufacturing and placing on the market may apply.
Classification Intentional
Category Listed under Annex A
Year of Listing Decision 2001
Persistence Can last up to 14 years or more in the soil
Specific exemptions associated with its use Production: None
Acceptable purposes associated with its use It was used as an insecticide, rodenticide and piscicide.
Conventions on POPs Stockholm Convention
Convention on Long-Range Transboundary Air Pollution
Rotterdam Convention
Basel Convention

Name

Endrin

Synonyms Endricol
CAS 72-20-8
Mendrin
rel-(1aR,2R,2aR,3R,6S,6aS,7S,7aS)-3,4,5,6,9,9-Hexachloro-1a,2,2a,3,6,6a,7,7a-octahydro-2,7:3,6-dimethanonaphtho[2,3-b]oxirene
1,4:5,8-Dimethanonaphthalene, 1,2,3,4,10,10-hexachloro-6,7-epoxy-1,4,4a,5,6,7,8,8a-octahydro-, endo,endo-
1,2,3,4,10,10-Hexachloro-6,7-epoxy-1,4,4a,5,6,7,8,8a-octahydro-endo-1,4-endo-5,8-dimethanonaphthalene
Endrex
2,7:3,6-Dimethanonaphth[2,3-b]oxirene, 3,4,5,6,9,9-hexachloro-1a,2,2a,3,6,6a,7,7a-octahydro-
Oktanex
Hexadrin
Hexachloroepoxyoctahydro-endo,endo-dimethanonapthalene
Nendrin
Structure

Molecular Formula: C12H8Cl6O
Molecular weight g/mol: 380.9 g/mol
SMILES: C1C2C3C(C1C4C2O4)C5(C(=C(C3(C5(Cl)Cl)Cl)Cl)Cl)Cl
Solubility in water: Insoluble

CAS Number 72-20-8
European Community (EC) Number 200-775-7
European Chemicals Agency (ECHA) 200-775-7
PubChem ID 12358480
DSSTOX Substance ID DTXSID6020561
KEGG C18124
ChemSpider 32815895

Similarity threshold Name of Related Compound DSSTox Substance ID CAS Number Molecular weight Molecular formula
1.0 Dieldrin DTXSID9020453 60-57-1 380 g/mol C12H8Cl6O
1.0 3,4,5,6,9,9-Hexachloro-1a,2,2a,3,6,6a,7,7a-octahydro-2,7:3,6-dimethanonaphtho[2,3-b]oxirene DTXSID3048150 128-10-9 380 g/mol C12H8Cl6O
1.0 11,12,13,14,17,17-hexachloro-5-oxaheptacyclo[7.6.1.13,7.111,14.02,8.04,6.010,15]octadec-12-ene(non-preferred name) DTXSID40289099 4802-29-3 447 g/mol C17H14Cl6O
0.98 3,4,5,6,9,9-Hexachloro-1a,2,2a,3,6,6a,7,7a-octahydro-2,7:3,6-dimethanonaphtho[2,3-b]oxiren-8-ol DTXSID60949729 26946-01-0 396 g/mol C12H8Cl6O2
0.97 MME DTXSID70903973 78185-58-7 382 g/mol C12H10Cl6O
0.97 3,4,5,6,8,8-Hexachloro-1a,7a-dimethyl-1a,2,2a,3,6,6a,7,7a-octahydro-3,6-methanonaphtho[2,3-b]oxirene DTXSID00994011 73292-20-3 396 g/mol C13H12Cl6O
0.95 2-(1,4,5,6,7,7-Hexachlorobicyclo[2.2.1]hept-5-en-2-yl)oxirane DTXSID40286240 28487-52-7 342 g/mol C9H6Cl6O
0.92 3,4,5,6-Tetrachloro-1a,2,2a,3,6,6a,7,7a-octahydro-2,7:3,6-dimethanonaphtho[2,3-b]oxirene DTXSID90991534 71221-14-2 312 g/mol C12H10Cl4O
0.92 1,5,6,7,8,8-Hexachloro-3-oxatricyclo[3.2.1.0~2,4~]oct-6-ene DTXSID60292141 89708-00-9 314 g/mol C7H2Cl6O
0.92 Endosulfan ether DTXSID0052704 3369-52-6 342 g/mol C9H6Cl6O
N/A Full List of similar compounds N/A N/A N/A g/mol N/A

Description Reference Article Link
Endrin was first used in 1951. Its applications were similar to those of aldrin and dieldrin, but endrin was not used for termite-proofing. Endrin turned out to be particularly effective against pests on cotton and in the tropics. Endrin is much more toxic to non-target species than aldrin and dieldrin and, consequently, its uses in the United States, where endrin was used almost entirely in the southeast, were voluntarily canceled in 1986. It seems that endrin is no longer produced anywhere in the world. However, a Material Safety Data Sheet ‘Endrin-methyl parathion 1.6–1.6 emulsive cotton spray insecticide’, revised on September 16, 1999 is in the ChemWeb.com database. Zitko. 2002. Chlorinated Pesticides: Aldrin, DDT, Endrin, Dieldrin, Mirex. Link
Endrin is an organochloride with the chemical formula C12H8Cl6O that was first produced in 1950 by Shell and Velsicol Chemical Corporation. It was primarily used as an insecticide, as well as a rodenticide and piscicide. It is a colourless, odorless solid, although commercial samples are often off-white. Endrin was manufactured as an emulsifiable solution known commercially as Endrex. The compound became infamous as a persistent organic pollutant and for this reason it is banned in many countries. In the environment endrin exists as either endrin aldehyde or endrin ketone and can be found mainly in bottom sediments of bodies of water. Wikipedia. Accessed 13 October 2020 Link
This insecticide is sprayed on the leaves of crops such as cotton and grains. It is also used to control rodents such as mice and voles. Animals can metabolize endrin, so it does not accumulate in their fatty tissue to the extent as other chemicals do. It has a long half-life, however, persisting in the soil for up to 12 years. Thakur and Pathania. 2020. Environmental fate of organic pollutants and effect on human health. Link
Endrin (CAS 72-20-8) is a synthetic organochlorine insecticide, rodenticide, and avicide, that was used primarily on cotton, rice, sugar cane, maize, as well as other crops. It is lipophilic and persistent in soils, with a half-life of up to 12 years. Although bioconcentration factors can range from 14 to 49 000, biomagnification is not significant. Honeycutt and Jones. 2014. Endrin Link