Enzymes are biological catalysts that facilitate the biotransformation of organic compounds, into (ideally) harmless products by favorable conditions that lower the activation energy of the reaction. This section of the database presents information on biodegradative enzymes involved in the biodegradation of POPs into (ideally) simple and non-toxic end products.
Use the filter feature to select the enzyme of interest.
| Enzyme name | EC number | Enzyme class | Encoding gene | Detailed information |
|---|---|---|---|---|
| Gamma-hexachlorocyclohexane dehydrochlorinase | 4.5.1.B1 | Lyases | LinA | link |
| 1,3,4,6-tetrachloro-1,4-cyclohexadiene hydrolase | 3.8.1.5 | Hydrolases | LinB | link |
| 2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase | 1.1.1.- | Oxidoreductases | LinC | link |
| 2,5-dichlorohydroquinone reductive dechlorinase | 2.5.1.- | Transferases | LinD | link |
| Hydroquinone 1,2-dioxygenase | 1.13.11.66 | Oxidoreductases | LinE | link |
| Maleylacetate reductase | 1.3.1.32 | Oxidoreductases | LinF | link |
| 3-oxoadipate CoA-transferase | 2.8.3.6 | Transferases | LinG | link |
| acetyl-CoA acetyltransferase | 2.3.1.9 | Transferases | LinJ | link |
| Reductive dehalogenase | N/A | Oxidoreductases | CCR98_02005 (PbrA) | link |
| Reductive dehalogenase | N/A | Oxidoreductases | CCR98_19135 (RhdA) | link |
| Alpha/beta hydrolase | N/A | Hydrolases | CCR98_00905 | link |
| Dioxygenase | N/A | Oxidoreductase | CCR98_02495 | link |
| DDT-dehydrochlorinase | 4.5.1.1 | Lyases | dhl1 | link |
| Ribonucleotide reductase activating transmembrane protein | 1.97.1.4 | Oxidoreductases | rrat | link |
| DDMU reductase | 1.3.-.- | Oxidoreductases | sds | link |
| DDA decarboxylase | 4.1.1.- | Lyases | dcl | link |
| OHCTT hydrolase | 3.7.1.25 | Hydrolases | hdl | link |
| Reductive dehalogenase | 4.2.1.3 | Lyases | rdh | link |
| DDD dehydrochlorinase | N/A | Oxidoreductases | dhc | link |
| Putative haloalkane dehalogenase | 3.8.1.5 | Hydrolases | dhg | link |
| DDNU hydratase | 4.2.1.2 | Lyases | hdt | link |
| biphenyl 2,3-dioxygenase | 1.14.12.18 | Oxidoreductases | bph | link |
| cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase | 1.3.1.56 | Oxidoreductases | bphB | link |
| Biphenyl-2,3-diol 1,2-dioxygenase | 1.13.11.39 | Oxidoreductases | bphC | link |
| 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase (HOPDA hydrolase) | 3.7.1.8 | Hydrolases | bph | link |
| 2-hydroxypenta-2,4-dienoate hydratase | 4.2.1.80 | Lyases | bhp | link |
| 4-hydroxy-2-oxovalerate aldolase | EC 4.1.3.39 | Lyases | bhp | link |
| Endosulfan sulfate monooxygenase | 1.14.14.- | Oxidoreductases | ese | link |
| Endosulfan monooxygenase | N/A | Oxidoreductases | N/A | link |
| Endosulfan sulfate hydrolase | N/A | Hydrolases | N/A | link |
| Endosulfan hemisulfate sulfatase | N/A | Hydrolases | N/A | link |
| Endosulfan diol dehydrogenase | N/A | Oxidoreductases | N/A | link |
| Endosulfan diol hydrolyase | N/A | Hydrolases | N/A | link |
| Endosulfan ether monooxygenase | N/A | Oxidoreductases | N/A | link |
| Endosulfan monooxygenase II | N/A | Oxidoreductases | N/A | link |
| Endosulfan hydroxyether dehydrogenase | N/A | Oxidoreductases | N/A | link |
| Endosulfan lactone lactonase | N/A | Hydrolases | N/A | link |
| 2-haloalkanoic acid dehalogenase | 4.5.1.B1 | Lyases | LinA | link |
| Epoxide hydrolase (haloacid dehalogenase) | 3.8.1.2 | Hydrolases | RPYSC3_28180 | link |
| Cytochrome p450 | N/A | Oxidoreductases | RPYSC3_18690 | link |
| Protocatechuate 4,5-dioxygenase | 1.13.11.8 | Oxidoreductases | ligA | link |
| Glutathione S-transferase | 2.5.1.18 | Transferase | gstA | link |
| Hexachlorobenzene oxidative dehalogenase | N/A | Oxidoreductases | hcbA | link |
| 4-hydroxyphenylacetate 3-hydroxylase | N/A | add | hcbB | link |
| Chlorobenzene reductive dehalogenase | 1.17.99.6 | Oxidoreductases | cbrA | link |
| 2,6-dichloro-p-hydroquinone 1,2-dioxygenase | 1.13.11.66 | Oxidoreductases | pcpA | link |
| pentachlorophenol-4-monooxygenase | 1.14.13.50 | Oxidoreductases | pcpB | link |
| tetrachloro-p-hydroquinone reductive dehalogenase | 1.21.4.5 | Oxidoreductases | PcpC | link |
| pentachlorophenol 4-monooxygenase reductase | 1.1.1.404 | Oxidoreductases | pcpD | link |
| chloromaleylacetate reductase | 1.3.1.32 | Oxidoreductases | pcpE | link |
| ortho-chlorophenol reductive dehalogenase | 3.8.1.- | Hydrolases | crpA | link |
| GroEL-type chaperonin | N/A | N/A | cprD | link |
| Tetrachloroethene reductive dehalogenase | 1.21.99.5 | Oxidoreductases | pceA | link |
| Fluoroacetate dehalogenase | 3.8.1.3 | Hydrolases | dehH | link |
| Benzoate dioxygenase | 1.14.12.10 | Oxidoreductases | ben | link |
| Benzoate dioxygenase - ferredoxin reductase | 1.18.1.3 | Oxidoreductases | benC | link |
| cis-diol dehydrogenase | 1.3.1.25 | Oxidoreductases | benD | link |
| Catechol 1,2-dioxygenase | 1.13.11.1 | Oxidoreductases | catA | link |
| Muconate cycloisomerase | 5.5.1.1 | Isomerases | catB | link |
| Muconolactone Delta-isomerase | 5.3.3.4 | Isomerases | catC | link |
| 3-oxoadipate CoA-transferase | 2.8.3.6 | Transferases | catIJ | link |
| beta-ketoadipyl CoA thiolase | 2.3.1.174 | Transferases | catF | link |
| beta-ketoadipate enol-lactone hydrolase | 3.1.1.24 | Hydrolases | catD | link |
| 4-chlorobenzoate CoA ligase | 6.2.1.33 | Ligases | fcbA | link |
| 4-chlorobenzoyl CoA dehalogenase | 3.8.1.7 | Hydrolase | fcbB | link |
| 4-chlorobenzoyl CoA thioesterase | 3.1.2.23 | Hydrolases | fcbC | link |
| Dibenzofuran dioxygenase | 1.14.12.- | Oxidoreductases | dfdAabcd | link |
| 2,2',3-trihydroxybiphenyl 1,2-dioxygenase | N/A | Oxidoreductases | dfdB | link |
| 2-hydroxy-6-(2'-hydroxyphenyl)-6-oxohexa-2,4-dienoic acid hydrolase dioxin dioxygenase | 3.7.1.13 | Hydrolases | dfdC | link |
| dioxin dioxygenase | 1.14.12.- | Oxidoreductases | dxnA | link |
| Dioxin hydrolase | 3.7.1.- | Hydrolases | dxnB | link |
| 2.4-dihydroxybenzoate monooxygenase | 1.14.14.- | Oxidoreductases | dxnD | link |
| hydroxyquinol 1,2-dioxygenase | 1.13.11.37 | Oxidoreductases | dxnF | link |
| 3-oxoadipate CoA-transferase | 2.8.3.6 | Transferases | dxnGH | link |
| acetyl CoA acetyltransferase | N/A | Transferases | dxnI | link |
| 1,1a-dihydroxy-1-hydro-9-fluorenone dehydrogenase | 1.1.1.256 | Oxidoreductases | flnB | link |
| short-chain dehydrogenase/reductase | N/A | Oxidoreductases | flnC | link |
| extradiol dioxygenase | N/A | Oxidoreductases | flnD | link |
| meta cleavage compound hydrolase | 3.7.1.- | Hydrolases | flnE | link |
| terminal dioxygenase | 1.14.12.13 | Oxidoreductases | narA | link |
| cis-dihydrodiol dehydrogenase | 1.3.1.29 | Oxidoreductases | narB | link |
| trans-o-hydroxybenzylidenepyruvate hydratase-aldolase | 4.1.2.45 | Lyases | narC | link |
| Lignin peroxidase | 1.14.14.- | Oxidoreductases | PcCYP | link |
| Naphthalene 1,2-dioxygenase | 1.18.1.7##1.18.1.7##1.14.12.12##1.14.12.12 | Oxidoreductases | nahA##nahA##nahA##nahA | link |
| cis-naphthalene dihydrodiol dehydrogenase | 1.3.1.29 | Oxidoreductases | nahB | link |
| 1,2-dihydroxynaphthalene dioxygenase | 1.13.11.56 | Oxidoreductases | nahC | link |
| 2-hydroxychromene-2-carboxylate dehydrogenase | 5.99.1.4 | Isomerases | nahD | link |
| 1,2-dihydroxybenzyl pyruvate aldolase | 4.1.2.45 | Lyases | nahE | link |
| salicylaldehyde dehydrogenase | 1.2.1.65 | Oxidoreductases | nahF | link |
| salicylate-5-hydroxylase | 1.14.13.172 | Oxidoreductases | nahGH##nahGH | link |
| 2-hydroxymuconicsemialdehyde dehydrogenase | 1.13.11.4 | Oxidoreductases | nahI | link |
| 4-oxalocrotonate tautomerase | 5.3.2.2 | Isomerases | nahJ | link |
| 2-oxo-3-hexenedioate decarboxylase | 4.1.1.77 | Lyases | nahK | link |
| 2-oxopent-4-enoate hydratase | 4.2.1.80 | Lyases | nahL | link |
| 4-hydroxy-2-oxovalerate aldolase | 4.1.3.39 | Lyases | nahM | link |
| 2-hydroxymuconic semialdehyde hydrolase | 3.7.1.9 | Hydrolases | nahN | link |
| acetaldehyde dehydrogenase | 1.2.1.10 | Oxidoreductases | nahO | link |
| Laccase | 1.10.3.2 | Oxidoreductases | lcc2304 | link |
| Gamma hexachlorocyclohexane dehydrochlorinase 2 | 4.5.1.B1 | Lyases | linA2 | link |
| Haloalkane dehalogenase | 3.8.1.5 | Hydrolases | linB | link |
| Enzyme name | EC number | Enzyme class | Encoding gene | Detailed information |