| Enzyme name | 2-hydroxymuconicsemialdehyde dehydrogenase |
| Description | oxidoreductase activity |
| Synonyms |
nahI nagI Gentisate 1,2-dioxygenase 2,5-dihydroxybenzoate dioxygenase gentisic acid oxidase gentisate dioxygenase |
| Degradation pathway |
Polychlorinated dibenzofurans (PCDF) biodegradation |
| Reaction catalyzed by enzyme |
2,5-dihydroxybenzoate + O(2) <=> maleylpyruvate |
| Enzyme class | Oxidoreductases |
| BRENDA | EC 1.13.11.4 |
| KEGG Orthology ID | K00450 |
| expasy | EC 1.13.11.4 |
| Enzyme Database | EC 1.13.11.4 |
| Organism |
Ralstonia sp. U2 |
| Status |
Reviewed |
| Encoding gene | nahI |
| Gene cluster | nahABCDEFGHIJKLMNO |
| subnit |
N/A |
| Protein Name |
Gentisate 1,2-dioxygenase |
| GenBank ID |
AF036940.2 |
| Protein ID |
AAD12619.1 |
| UniProtKB ID |
O86041 |
| Author | Zhou et al., 2001 |
| Title | nag genes of Ralstonia (formerly Pseudomonas) sp. strain U2 encoding enzymes for gentisate catabolism |
| PMID | 11133965.0 |
| Pubmed Link | Link |
| Research Link | Link |
| Author | Liu et al., 2011 |
| Title | Functional characterization of a gene cluster involved in gentisate catabolism in Rhodococcus sp. strain NCIMB 12038 |
| PMID | 21181154.0 |
| Pubmed Link | Link |
| Research Link | Link |
| Author | Izmalkova et al., 2013 |
| Title | The organization of naphthalene degradation genes in Pseudomonas putida strain AK5 |
| PMID | 23266498.0 |
| Pubmed Link | Link |
| Research Link | Link |