Enzyme name | Fluoroacetate dehalogenase |
Description | DehH1 acts predominantly on fluoroacetate, dehH2 acts on chloro-, bromo- and iodoacetate, but not on fluoroacetate |
Synonyms |
haloacetate dehalogenase H-1 dehH1 dehH2 monohaloacetate dehalogenase haloacetate halidohydrolase fluoroacetate dehalogenase haloacid dehalogenase |
Degradation pathway |
Perfluorooctane Sulfonate (PFOS) biodegradation Perfluorooctanoic Acid (PFOA) biodegradation |
Reaction catalyzed by enzyme |
haloacetate + H2O <=> glycolate + halide |
Enzyme class | Hydrolases |
BRENDA | EC 3.8.1.3 |
KEGG Orthology ID | K01561 |
expasy | EC 3.8.1.3 |
Enzyme Database | EC 3.8.1.3 |
Organism |
Moraxella sp. B Moraxella sp. B |
Status |
Reviewed Reviewed |
Encoding gene | dehH |
Gene cluster | N/A |
subnit |
dehH1 dehH2 |
Protein Name |
Haloacetate dehalogenase H-1 haloacetate dehalogenase H-2 |
GenBank ID |
D90422.1 D90423.1 |
Protein ID |
BAA14412.1 BAA14413.1 |
UniProtKB ID |
Q01398 Q01399 |
Author | Kawasaki et al., 1992 |
Title | Lack of homology between two haloacetate dehalogenase genes encoded on a plasmid from Moraxella sp. strain B |
PMID | 1512562.0 |
Pubmed Link | Link |
Research Link | Link |
Author | Donnelly and Murphy. 2009 |
Title | Purification and properties of fluoroacetate dehalogenase from Pseudomonas fluorescens DSM 8341 |
PMID | 18807226.0 |
Pubmed Link | Link |
Research Link | Link |