| Enzyme name | 4-chlorobenzoate CoA ligase |
| Description | Activates 4-chlorobenzoate to 4-chlorobenzoate CoA |
| Synonyms |
fcbA 4-chlorobenzoate:CoA ligase 4-chlorobenzoate—CoA ligase 4-CB:CoA ligase 4-Chlorobenzoyl-coenzyme A ligase |
| Degradation pathway |
Perfluorooctane Sulfonate (PFOS) biodegradation Perfluorooctanoic Acid (PFOA) biodegradation |
| Reaction catalyzed by enzyme |
4-chlorobenzoate + CoA + ATP <=> 4-chlorobenzoyl-CoA + AMP + diphosphate |
| Enzyme class | Ligases |
| BRENDA | EC 6.2.1.33 |
| KEGG Orthology ID | K14417 |
| expasy | EC 6.2.1.33 |
| Enzyme Database | EC 6.2.1.33 |
| Organism |
Arthrobacter sp. FG1 |
| Status |
Unreviewed |
| Encoding gene | fcbA |
| Gene cluster | fcbABC |
| subnit |
N/A |
| Protein Name |
4-chlorobenzoate CoA ligase |
| GenBank ID |
AM231748.2 |
| Protein ID |
CAJ77821.2 |
| UniProtKB ID |
Q2A655 |
| Author | Radice et al., 2007 |
| Title | Cloning of the Arthrobacter sp. FG1 dehalogenase genes and construction of hybrid pathways in Pseudomonas putida strains |
| PMID | 17384944 |
| Pubmed Link | Link |
| Research Link | Link |
| Author | Chang et al., 1992 |
| Title | Isolation and characterization of the three polypeptide components of 4-chlorobenzoate dehalogenase from Pseudomonas sp. strain CBS-3 |
| PMID | 1610806 |
| Pubmed Link | Link |
| Research Link | Link |
| Author | Zhou et al., 2004 |
| Title | The purification and characterisation of 4-chlorobenzoate:CoA ligase and 4-chlorobenzoyl CoA dehalogenase from Arthrobacter sp. strain TM-1 |
| PMID | 15068371 |
| Pubmed Link | Link |
| Research Link | Link |
| Author | Crooks and Copley. 1994 |
| Title | Purification and characterization of 4-chlorobenzoyl CoA dehalogenase from Arthrobacter sp. strain 4-CB1 |
| PMID | 7918379 |
| Pubmed Link | Link |
| Research Link | Link |