Enzyme name 2-hydroxychromene-2-carboxylate dehydrogenase
Description This enzyme is involved in naphthalene degradation.
Synonyms nahD
2-hydroxychromene-2-carboxylic acid isomerase
2HC2CA isomerase
Degradation pathway Polychlorinated dibenzofurans (PCDF) biodegradation
Reaction catalyzed by enzyme 2-hydroxychromene-2-carboxylate <=> (3E)-4-(2-hydroxyphenyl)-2-oxobut-3-enoate
Enzyme class Isomerases

BRENDA EC 5.99.1.4
KEGG Orthology ID K14584 
expasy EC 5.99.1.4
Enzyme Database EC 5.99.1.4
Organism Pseudomonas putida ND6
Status Unreviewed
Encoding gene nahD
Gene cluster nahABCDEFGHIJKLMNO
subnit N/A
Protein Name 2-hydroxychromene-2-carboxylate isomerase
GenBank ID AY208917.2
Protein ID AAP44193.1
UniProtKB ID Q6XUU2

Author Thompson et al., 2007
Title 2-Hydroxychromene-2-carboxylic acid isomerase: a kappa class glutathione transferase from Pseudomonas putida
PMID 17508726
Pubmed Link Link
Research Link Link
Author Ohmoto et al., 1998
Title Purification and some properties of 2-hydroxychromene-2-carboxylate isomerase from naphthalenesulfonate-assimilating Pseudomonas sp. TA-2
PMID 9722670
Pubmed Link Link
Research Link Link
Author Keck et al., 2006
Title Identification and functional analysis of the genes for naphthalenesulfonate catabolism by Sphingomonas xenophaga BN6
PMID 16804169
Pubmed Link Link
Research Link Link