| Enzyme name | pentachlorophenol 4-monooxygenase reductase |
| Description | Catalyzes the reduction of tetrachlorobenzoquinone (TCBQ) to yield tetrachlorohydroquinone (TCHQ) |
| Synonyms |
TCBQ reductase pcpD 2,3,5,6-tetrachlorobenzoquinone reductase pentachlorophenol 4-monooxygenase reductase |
| Degradation pathway |
Hexachlorobenzene biodegradation Pentachlorobenzene biodegradation Pentachlorophenol biodegradation |
| Reaction catalyzed by enzyme |
2,3,5,6-tetrachlorohydroquinone + NAD(+) <=> 2,3,5,6-tetrachloro-1,4-benzoquinone + NADH |
| Enzyme class | Oxidoreductases |
| BRENDA | EC 1.1.1.404 |
| KEGG Orthology ID | K21607 |
| expasy | EC 1.1.1.404 |
| Enzyme Database | EC 1.1.1.404 |
| Organism |
Sphingomonas sp. UG30 |
| Status |
Unreviewed |
| Encoding gene | pcpD |
| Gene cluster | pcpABCDE |
| subnit |
N/A |
| Protein Name |
pentachlorophenol 4-monooxygenase reductase |
| GenBank ID |
AF059680.1 |
| Protein ID |
AAC15880.1 |
| UniProtKB ID |
O68978 |
| Author | Chen and Yang. 2008 |
| Title | Biochemical characterization of the tetrachlorobenzoquinone reductase involved in the biodegradation of pentachlorophenol |
| PMID | 19325743 |
| Pubmed Link | Link |
| Research Link | Link |
| Author | Yadid et al., 2013 |
| Title | Sequestration of a highly reactive intermediate in an evolving pathway for degradation of pentachlorophenol |
| PMID | 23676275 |
| Pubmed Link | Link |
| Research Link | Link |
| Author | Dai et al., 2003 |
| Title | A previously unrecognized step in pentachlorophenol degradation in Sphingobium chlorophenolicum is catalyzed by tetrachlorobenzoquinone reductase (PcpD) |
| PMID | 12486067 |
| Pubmed Link | Link |
| Research Link | Link |
| Author | Su et al., 2008 |
| Title | The Catalytic Product of Pentachlorophenol 4-Monooxygenase is Tetra-chlorohydroquinone rather than Tetrachlorobenzoquinone |
| PMID | 19088919 |
| Pubmed Link | Link |
| Research Link | Link |