| Enzyme name | 4-hydroxy-2-oxovalerate aldolase |
| Description | Lyase activity |
| Synonyms |
nahM 4-hydroxy-2-oxovalerate pyruvate-lyase 4-hydroxy-2-ketovalerate aldolase 4-hydroxy-2-oxopentanoate pyruvate-lyase (acetaldehyde-forming) |
| Degradation pathway |
Polychlorinated dibenzofurans (PCDF) biodegradation |
| Reaction catalyzed by enzyme |
(S)-4-hydroxy-2-oxopentanoate <=> acetaldehyde + pyruvate |
| Enzyme class | Lyases |
| BRENDA | EC 4.1.3.39 |
| KEGG Orthology ID | K18365 |
| expasy | EC 4.1.3.39 |
| Enzyme Database | EC 4.1.3.39 |
| Organism |
Pseudomonas putida NCIB 9816-4 |
| Status |
Unreviewed |
| Encoding gene | nahM |
| Gene cluster | nahABCDEFGHIJKLMNO |
| subnit |
N/A |
| Protein Name |
4-hydroxy-2-oxovalerate aldolase |
| GenBank ID |
AF491307.2 |
| Protein ID |
AAO64300.1 |
| UniProtKB ID |
Q7B7H0 |
| Author | Baker et al., 2012 |
| Title | Protein-protein interactions and substrate channeling in orthologous and chimeric aldolase-dehydrogenase complexes |
| PMID | 22316175.0 |
| Pubmed Link | Link |
| Research Link | Link |
| Author | Manjasetty et al., 2001 |
| Title | Crystallization and preliminary X-ray analysis of dmpFG-encoded 4-hydroxy-2-ketovalerate aldolase--aldehyde dehydrogenase (acylating) from Pseudomonas sp. strain CF600 |
| PMID | 11264589.0 |
| Pubmed Link | Link |
| Research Link | Link |
| Author | Powlowski et al., 1993 |
| Title | Purification and properties of the physically associated meta-cleavage pathway enzymes 4-hydroxy-2-ketovalerate aldolase and aldehyde dehydrogenase (acylating) from Pseudomonas sp. strain CF600 |
| PMID | 8419288.0 |
| Pubmed Link | Link |
| Research Link | Link |