| Enzyme name | biphenyl 2,3-dioxygenase |
| Description | dioxygenation of DDT |
| Synonyms |
biphenyl dioxygenase 2,3-biphenyl dioxygenase oxygen oxidoreductase (2,3-hydroxylating) Biphenyl 2,3-dioxygenase |
| Degradation pathway |
DDT degradation |
| Reaction catalyzed by enzyme |
biphenyl + NADH + H+ + O2 <=> (1S,2R)-3-phenylcyclohexa-3,5-diene-1,2-diol + NAD+ |
| Enzyme class | Oxidoreductases |
| BRENDA | EC 1.14.12.18 |
| KEGG Orthology ID | K08689 |
| expasy | EC 1.14.12.18 |
| Enzyme Database | EC 1.14.12.18 |
| Organism |
Rhodococcus jostii Rhodococcus jostii Rhodococcus jostii Rhodococcus jostii |
| Status |
Reviewed Reviewed Reviewed Reviewed |
| Encoding gene | bph |
| Gene cluster | bhpABCDEF |
| subnit |
bphA1 bphA2 bphA3 bphA4 |
| Protein Name |
biphenyl 2,3-dioxygenase subunit alpha Biphenyl 2,3-dioxygenase subunit beta Biphenyl 2,3-dioxygenase, ferredoxin component Biphenyl 2,3-dioxygenase, ferredoxin reductase component |
| GenBank ID |
D32142 D32142 D32142 D32142 |
| Protein ID |
BAA06868.1 BAA06869.1 BAA06870.1 BAA06871.1 |
| UniProtKB ID |
Q53122 Q53123 Q53124 Q0S032 |
| Author | Masai et al., 1995 |
| Title | Characterization of biphenyl catabolic genes of gram-positive polychlorinated biphenyl degrader Rhodococcus sp. strain RHA1 |
| PMID | 7793929 |
| Pubmed Link | Link |
| Research Link | Link |
| Author | Yamada et al., 1998 |
| Title | Two nearly identical aromatic compound hydrolase genes in a strong polychlorinated biphenyl degrader, Rhodococcus sp. strain RHA1 |
| PMID | 9603807 |
| Pubmed Link | Link |
| Research Link | Link |
| Author | Yang et al., 2007 |
| Title | Characterization and functional analysis of a novel gene cluster involved in biphenyl degradation in Rhodococcus sp. strain R04 |
| PMID | 18045404 |
| Pubmed Link | Link |
| Research Link | Link |
| Author | Masai et al., 1997 |
| Title | The bphDEF meta-cleavage pathway genes involved in biphenyl/polychlorinated biphenyl degradation are located on a linear plasmid and separated from the initial bphACB genes in Rhodococcus sp. strain RHA1 |
| PMID | 9073078 |
| Pubmed Link | Link |
| Research Link | Link |