| Enzyme name | salicylate-5-hydroxylase |
| Description | oxidoreductase activity |
| Synonyms |
salicylate hydroxylase salicylate 1-monooxygenase Salicylate 1-hydroxylase salicylate-5-hydroxylase large oxygenase component |
| Degradation pathway |
Polychlorinated dibenzofurans (PCDF) biodegradation |
| Reaction catalyzed by enzyme |
Salicylate + NADH + O(2) <=> 2,5-dihydroxybenzoate + NAD(+) + H(2)O |
| Enzyme class | Oxidoreductases |
| BRENDA | EC 1.14.13.172##EC 1.14.13.172 |
| KEGG Orthology ID | K18242 ##K18243 |
| expasy | EC 1.14.13.172##EC 1.14.13.172 |
| Enzyme Database | EC 1.14.13.172##EC 1.14.13.172 |
| Organism |
Ralstonia sp. U2 Ralstonia sp. U2 |
| Status |
Reviewed Reviewed |
| Encoding gene | nahGH##nahGH |
| Gene cluster | nahABCDEFGHIJKLMNO##nahABCDEFGHIJKLMNO |
| subnit |
nagG nagH |
| Protein Name |
salicylate-5-hydroxylase large oxygenase component salicylate-5-hydroxylase small oxygenase component |
| GenBank ID |
AF036940.2 AF036940.2 |
| Protein ID |
AAD12607.1 AAD12608.1 |
| UniProtKB ID |
O52379 O52380 |
| Author | Fuenmayor et al., 1998 |
| Title | A gene cluster encoding steps in conversion of naphthalene to gentisate in Pseudomonas sp. strain U2 |
| PMID | 9573207.0 |
| Pubmed Link | Link |
| Research Link | Link |
| Author | Zhou et al., 2002 |
| Title | Salicylate 5-hydroxylase from Ralstonia sp. strain U2: a monooxygenase with close relationships to and shared electron transport proteins with naphthalene dioxygenase |
| PMID | 11872705.0 |
| Pubmed Link | Link |
| Research Link | Link |
| Author | Hou et al., 2021 |
| Title | Structural and Biochemical Analysis Reveals a Distinct Catalytic Site of Salicylate 5-Monooxygenase NagGH from Rieske Dioxygenases |
| PMID | 33452034.0 |
| Pubmed Link | Link |
| Research Link | Link |