| Enzyme name | 4-chlorobenzoyl CoA dehalogenase |
| Description | Specific for dehalogenation at the 4-position. Can dehalogenate substrates bearing fluorine, chlorine, bromine and iodine in the 4-position |
| Synonyms |
4-chlorobenzoyl-CoA dehalogenase 4-chlorobenzoate-CoA-dehalogenase dehalogenase chd fcbB |
| Degradation pathway |
Perfluorooctane Sulfonate (PFOS) biodegradation Perfluorooctanoic Acid (PFOA) biodegradation |
| Reaction catalyzed by enzyme |
4-chlorobenzoyl-CoA + H(2)O <=> 4-hydroxybenzoyl CoA + chloride |
| Enzyme class | Hydrolase |
| BRENDA | EC 3.8.1.7 |
| KEGG Orthology ID | K14418 |
| expasy | EC 3.8.1.7 |
| Enzyme Database | EC 3.8.1.7 |
| Organism |
Arthrobacter sp. FG1 |
| Status |
Unreviewed |
| Encoding gene | fcbB |
| Gene cluster | fcbABC |
| subnit |
N/A |
| Protein Name |
4-chlorobenzoyl CoA dehalogenase |
| GenBank ID |
AM231748.2 |
| Protein ID |
CAJ77822.1 |
| UniProtKB ID |
Q2A654 |
| Author | Radice et al., 2007 |
| Title | Cloning of the Arthrobacter sp. FG1 dehalogenase genes and construction of hybrid pathways in Pseudomonas putida strains |
| PMID | 17384944 |
| Pubmed Link | Link |
| Research Link | Link |
| Author | Chang et al., 1992 |
| Title | Isolation and characterization of the three polypeptide components of 4-chlorobenzoate dehalogenase from Pseudomonas sp. strain CBS-3 |
| PMID | 1610806 |
| Pubmed Link | Link |
| Research Link | Link |
| Author | Zhou et al., 2004 |
| Title | The purification and characterisation of 4-chlorobenzoate:CoA ligase and 4-chlorobenzoyl CoA dehalogenase from Arthrobacter sp. strain TM-1 |
| PMID | 15068371 |
| Pubmed Link | Link |
| Research Link | Link |
| Author | Crooks and Copley. 1994 |
| Title | Purification and characterization of 4-chlorobenzoyl CoA dehalogenase from Arthrobacter sp. strain 4-CB1 |
| PMID | 7918379 |
| Pubmed Link | Link |
| Research Link | Link |