| Enzyme name | tetrachloro-p-hydroquinone reductive dehalogenase |
| Description | Sequential reduction of tetrachloro-p-hydroquinone to dichloro-p-hydroquinonem using glutathione as the reducing agent |
| Synonyms |
tetrachloro-p-hydroquinone reductive dehalogenase pcpC glutathione disulfide:2,6-dichlorohydroquinone (chlorinating) |
| Degradation pathway |
Hexachlorobenzene biodegradation Pentachlorobenzene biodegradation Pentachlorophenol biodegradation |
| Reaction catalyzed by enzyme |
2,6-dichlorohydroquinone + Cl(-) + glutathione disulfide <=> 2,3,6-trichlorohydroquinone + 2 glutathione 2,3,6-trichlorohydroquinone + chloride + glutathione disulfide <=> 2,3,5,6-tetrachlorohydroquinone |
| Enzyme class | Oxidoreductases |
| BRENDA | EC 1.21.4.5 |
| KEGG Orthology ID | K15241 |
| expasy | EC 1.21.4.5 |
| Enzyme Database | EC 1.21.4.5 |
| Organism |
Sphingobium chlorophenolicum ATCC 39723 |
| Status |
Reviewed |
| Encoding gene | PcpC |
| Gene cluster | pcpABCDE |
| subnit |
N/A |
| Protein Name |
tetrachloro-p-hydroquinone reductive dehalogenase |
| GenBank ID |
AF512952.1 |
| Protein ID |
AAM96673.1 |
| UniProtKB ID |
Q03520 |
| Author | Cai and Xun. 2002 |
| Title | Organization and regulation of pentachlorophenol-degrading genes in Sphingobium chlorophenolicum ATCC 39723 |
| PMID | 12169590 |
| Pubmed Link | Link |
| Research Link | Link |
| Author | McCarthy et al., 1996 |
| Title | Exploration of the relationship between tetrachlorohydroquinone dehalogenase and the glutathione S-transferase superfamily |
| PMID | 8931562 |
| Pubmed Link | Link |
| Research Link | Link |
| Author | Xun et al., 1992 |
| Title | Purification and characterization of a tetrachloro-p-hydroquinone reductive dehalogenase from a Flavobacterium sp |
| PMID | 1459949 |
| Pubmed Link | Link |
| Research Link | Link |