| Enzyme name | 1,2-dihydroxybenzyl pyruvate aldolase |
| Description | Involved in the naphthalene upper catabolic pathway. Catalyzes the transformation of trans-O-hydroxybenzylidenepyruvate (THBPA) to salicylaldehyde and pyruvate. |
| Synonyms |
nahE 2-hydroxybenzalpyruvate aldolase trans-o-hydroxybenzylidenepyruvate Trans-O-hydroxybenzylidenepyruvate hydratase-aldolase |
| Degradation pathway |
Polychlorinated dibenzofurans (PCDF) biodegradation |
| Reaction catalyzed by enzyme |
(3E)-4-(2-hydroxyphenyl)-2-oxobut-3-enoate + H(2)O <=> salicylaldehyde + pyruvate |
| Enzyme class | Lyases |
| BRENDA | EC 4.1.2.45 |
| KEGG Orthology ID | K14585 |
| expasy | EC 4.1.2.45 |
| Enzyme Database | EC 4.1.2.45 |
| Organism |
Pseudomonas putida ND6 |
| Status |
Unreviewed |
| Encoding gene | nahE |
| Gene cluster | nahABCDEFGHIJKLMNO |
| subnit |
N/A |
| Protein Name |
1,2-dihydroxybenzyl pyruvate aldolase |
| GenBank ID |
AY208917.2 |
| Protein ID |
AAP44192.1 |
| UniProtKB ID |
Q6XUU3 |
| Author | Kuhm et al., 1993 |
| Title | Purification and properties of 2'-hydroxybenzalpyruvate aldolase from a bacterium that degrades naphthalenesulfonates |
| PMID | 8486638.0 |
| Pubmed Link | Link |
| Research Link | Link |
| Author | Keck et al., 2006 |
| Title | Identification and functional analysis of the genes for naphthalenesulfonate catabolism by Sphingomonas xenophaga BN6 |
| PMID | 16804169.0 |
| Pubmed Link | Link |
| Research Link | Link |
| Author | Eaton. 2000 |
| Title | trans-o-Hydroxybenzylidenepyruvate hydratase-aldolase as a biocatalyst |
| PMID | 10831455.0 |
| Pubmed Link | Link |
| Research Link | Link |