| Enzyme name | 2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase |
| Description | Catalyzes the dehydrogenation of 2,5-dichloro-2,5-cyclohexadiene-1,4-diol (2,5-DDOL) to 2,5-dichlorohydroquinone (2,5-DCHQ) |
| Synonyms |
2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase LinC LinC Oxidoreductase Short-chain alcohol dehydrogenase 2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase |
| Degradation pathway |
Alpha-hexachlorocyclohexane degradation Beta-hexachlorocyclohexane degradation Delta-hexachlorocyclohexane degradation Gamma-hexachlorocyclohexane degradation |
| Reaction catalyzed by enzyme |
2,5-dichloro-2,5-cyclohexadiene-1,4-diol (2,5-DDOL) + NAD+ <=> 2,5-dichloro-p-quinol + NADH + Hydrogen ions |
| Enzyme class | Oxidoreductases |
| BRENDA | EC 1.1.1.- |
| KEGG Orthology ID | SJA_C1-05590 |
| expasy | EC 1.1.1.- |
| Enzyme Database | EC 1.1.1 |
| Organism |
Sphingobium japonicum |
| Status |
Reviewed |
| Encoding gene | LinC |
| Gene cluster | LinABCDEFGHJ |
| subnit |
linC |
| Protein Name |
2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase |
| GenBank ID |
D14595.1 |
| Protein ID |
BAA03444.1 |
| UniProtKB ID |
D4YYG1 |
| Author | Nagata et al., 1994 |
| Title | Cloning and sequencing of a 2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase gene involved in the degradation of gamma-hexachlorocyclohexane in Pseudomonas paucimobilis |
| PMID | 7515041.0 |
| Pubmed Link | Link |
| Research Link | Link |
| Author | Zhang and Ciao. 2009 |
| Title | Isolation of Hexachlorocyclohexane-Degrading Sphingomonas sp. and Characterization of Lin Genes Responsible for the Biodegradation of Hexachlorocyclohexane |
| PMID | 25850427.0 |
| Pubmed Link | Link |
| Research Link | Link |