| Enzyme name | 2-hydroxypenta-2,4-dienoate hydratase |
| Description | Catalyzes the conversion of 2-hydroxypentadienoic acid (enolic form of 2-oxopent-4-enoate) to 4-hydroxy-2-ketopentanoic acid. |
| Synonyms |
2-hydroxypenta-2,4-dienoate hydratase bhpE HPD hydratase EC 4.2.1.80 2-hydroxypentadienoic acid hydratase MhpD |
| Degradation pathway |
DDT degradation |
| Reaction catalyzed by enzyme |
(S)-4-hydroxy-2-oxopentanoate <=> (2Z)-2-hydroxypenta-2,4-dienoate + H2OUniRule |
| Enzyme class | Lyases |
| BRENDA | EC 4.2.1.80 |
| KEGG Orthology ID | EC 4.2.1.80 |
| expasy | EC 4.2.1.80 |
| Enzyme Database | EC 4.2.1.80 |
| Organism |
Comamonas testosteroni |
| Status |
Reviewed |
| Encoding gene | bhp |
| Gene cluster | bhpABCDEF |
| subnit |
bhpE |
| Protein Name |
add |
| GenBank ID |
AB024335.1 |
| Protein ID |
BAA82880.1 |
| UniProtKB ID |
Q9S156 |
| Author | Masai et al., 1995 |
| Title | Characterization of biphenyl catabolic genes of gram-positive polychlorinated biphenyl degrader Rhodococcus sp. strain RHA1 |
| PMID | 7793929.0 |
| Pubmed Link | Link |
| Research Link | Link |
| Author | Yamada et al., 1998 |
| Title | Two nearly identical aromatic compound hydrolase genes in a strong polychlorinated biphenyl degrader, Rhodococcus sp. strain RHA1 |
| PMID | 9603807.0 |
| Pubmed Link | Link |
| Research Link | Link |
| Author | Yang et al., 2007 |
| Title | Characterization and functional analysis of a novel gene cluster involved in biphenyl degradation in Rhodococcus sp. strain R04 |
| PMID | 18045404.0 |
| Pubmed Link | Link |
| Research Link | Link |
| Author | Masai et al., 1997 |
| Title | The bphDEF meta-cleavage pathway genes involved in biphenyl/polychlorinated biphenyl degradation are located on a linear plasmid and separated from the initial bphACB genes in Rhodococcus sp. strain RHA1 |
| PMID | 9073078.0 |
| Pubmed Link | Link |
| Research Link | Link |