Enzyme name Dioxin hydrolase
Description hydrolase activity
Synonyms dxnB
Degradation pathway Polychlorinated dibenzofurans (PCDF) biodegradation
Polychlorinated dibenzo-p-dioxins (PCDD) biodegradation
Reaction catalyzed by enzyme dibenzo-p-dioxin + NADH + H+ + oxygen <=> 4,4a-dihydroxy-dihydro-dibenzo-p-dioxin + NAD+
Enzyme class Hydrolases

BRENDA EC 3.7.1.-
KEGG Orthology ID K22717
expasy EC 3.7.1.-
Enzyme Database EC 3.7.1.-
Organism Sphingomonas sp. strain RW1
Status Unreviewed
Encoding gene dxnB
Gene cluster dxnABCDEFGHI
subnit dxnB
Protein Name dioxin dioxygenase, large subunit
GenBank ID X72850.1
Protein ID CAA51367.1
UniProtKB ID O86901

Author Armengaud et al., 1998
Title Genetic analysis of dioxin dioxygenase of Sphingomonas sp. Strain RW1: catabolic genes dispersed on the genome
PMID 9683494
Pubmed Link Link
Research Link Link
Author Aly et al., 2008
Title Two angular dioxygenases contribute to the metabolic versatility of dibenzofuran-degrading Rhodococcus sp. strain HA01
PMID 18441103
Pubmed Link Link
Research Link Link
Author Wittich et al., 1992
Title Metabolism of dibenzo-p-dioxin by Sphingomonas sp. strain RW1. 
PMID 1575472
Pubmed Link Link
Research Link Link
Author Strubel et al., 1989
Title Enrichment of dibenzofuran utilizing bacteria with high co-metabolic potential towards dibenzodioxin and other anellated aromatics.
PMID 2744419
Pubmed Link Link
Research Link Link